Resonance calendar/eroom's law

Eroom's law is the observation that drug discovery is becoming slower and more expensive over time, despite improvements in technology (such as high-throughput screening, biotechnology, combinatorial chemistry, and computational drug design), a trend first observed in the 1980s. The inflation-adjusted cost of developing a new drug roughly doubles every nine years. In order to highlight the contrast with the exponential advancements of other forms of technology (such as transistors) over time, the name given to the observation is Moore's law spelled backwards.[2020 Bikepacking trip through Belgium]

The idea is that new tech will always have to compete with old tech. Therefore, the results of a new drug must be better 'significantly' than an older drug, a new rock band must be better than The Beatles. This idea was triggered by this article on lifescivc